Class HaplotypeProbabilityOfNormalGivenTumor

java.lang.Object
picard.fingerprint.HaplotypeProbabilities
picard.fingerprint.HaplotypeProbabilityOfNormalGivenTumor

public class HaplotypeProbabilityOfNormalGivenTumor extends HaplotypeProbabilities
A wrapper class for any HaplotypeProbabilities instance that will assume that the given evidence is that of a tumor sample and provide an hp for the normal sample that tumor came from. This models possible loss of heterozygosity where het genotypes turn into a homozygous genotype with probability pLoH.

The shortcoming of this model is that we assume that the events are all independent, but this way they are allowed.